Ultrasound Responsive Mn/Se‐Nanozyme as PANoptosis Initiators for Bladder Cancer Immunotherapy (Adv. Healthcare Mater. 17/2026)

PANoptosis. An ultrasound-activated FCS-coated Mn/Se nanozyme releases Mn and Se species upon acoustic stimulation. The generated catalytic ions induce PANoptosis and immune signaling, resulting in immunogenic remodeling of the tumor microenvironment and thereby enhancing efficient tumor destruction. More details can be found in the Research Article by Guanglin Huang, Xing Lu, Xiaoyong Zeng, and co-workers (DOI: 10.1002/adhm.202504808).