The influence of 9 non⁃pharmacological intervention methods on preoperative anxiety of surgical children:a network Meta⁃analysis

ObjectiveTo evaluate the effect of 9 non⁃pharmaceutical interventions on preoperative anxiety of surgical children by using Bayesian network Meta⁃analysis.MethodsThe PubMed，Web of Science，Cochrane Library，EMbase，China Biomedical Literature Database（CBM），China Knowledge Network（CNKI），WanFang Data and VIP Database（VIP） were retrieved by computer.The retrieval period was from the beginning of the establishment of the database to January 31，2021.Two researchers independently carried out literature screening and data extraction.WinBugs，Stata software were used for data analysis.ResultsA total of 44 randomized controlled trials were included，including 9 non⁃pharmacological intervention methods，with a total of 4405 children，and the quality of the included studies was grade A or B.The results of the network Meta⁃analysis showed that，compared with conventional nursing，interest induction，therapeutic games and distraction had statistically significant differences in the effect of preoperative anxiety intervention in children undergoing surgery（P<0.05）；Among the nine non⁃drug therapies included，there was a statistically significant difference in interest induction compared with clown therapy，virtual reality technology（VR），and music therapy（P<0.05），while there was no statistically significant difference in other interventions（P>0.05）.The SUCRA ranking probability chart showed that interest induction was the best intervention method for preoperative anxiety in children，with a probability of 94.2%，followed by therapeutic games 73.1% and distraction 64.1%.ConclusionCombining the results of mesh Meta⁃analysis and the SUCRA probability ranking，it is recommended that interest induction is a non⁃pharmacological intervention to relieve preoperative anxiety in children，followed by therapeutic games or distraction.