Lighting Up Arginine Metabolism Dynamics in Neural Differentiation through Ratiometric Fluorescence Imaging

-stimulated NSC differentiation. Further studies revealed that Arg-mediated activation of the mTORC1 pathway could coordinate qNSC reactivation and neuronal differentiation by regulating mitochondrial energy metabolism from glycolysis to mitochondrial oxidative phosphorylation. These findings not only enhanced our understanding of the metabolic pathways governing NSC differentiation but also offered new perspectives for neuroscience research and potential therapeutic interventions.