基因沉默
心脏纤维化
纤维化
核受体
生物
核受体辅活化子3
癌症研究
辅活化剂
受体
细胞生物学
纤维连接蛋白
化学
核受体辅活化子2
信号转导
基因表达
分子生物学
小干扰RNA
医学
基因
作者
Yawei Dai,Yong Li,Xiaoliang Yang,Yu Zhou,Yukang Mao,Yang Chuanxi,Peng Li,Kun Zhao
摘要
Overall, our finding identified that silencing Fn1 possessed beneficial effects against NaCl-induced cardiac fibrosis through downregulating the ferroptosis of NRCFs, which was attributed to the inhibition of NOCA4-mediated ferritinophagy.
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