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Updates in the use of cannabis for insomnia

大麻 失眠症 医学 精神科 大麻的影响 四氢大麻酚 大麻素 屈大麻酚 δ-9-四氢大麻酚 大麻酚 内科学 受体
作者
David C. Earl,Marco Proano
出处
期刊:Current Opinion in Pulmonary Medicine [Lippincott Williams & Wilkins]
卷期号:28 (6): 511-514 被引量:1
标识
DOI:10.1097/mcp.0000000000000914
摘要

This review aims to summarize recent updates in the area of cannabis use for insomnia.Cannabis products have continued to become more potent, particularly in regard to delta-9- tetrahydrocannabinol (THC) concentration. Additionally, the use of cannabis has continued to become more accepted with less legal restrictions. The reported use of cannabis for relief of symptoms in sleep disorders appears to be increasing, however the specific effects of cannabinoids on sleep varies with cannabinoid type and concentration. Some evidence supports claims of efficacy of cannabinoids in sleep disorders such as insomnia, while other evidence is either lacking or in some cases contradictory. Regular cannabis use has been associated with withdrawal which can profoundly alter sleep. Also, clinicians should be aware of the potential effects of cannabis on the metabolism of other medications as well as the fact that cannabis use has been reported in a significant number of women in the periods before, during, and after pregnancy.Cannabis use has been becoming more and more prevalent in the setting of relaxed restrictions and easier consumer level access to cannabis and cannabis products. A relative paucity of high quality evidence regarding the effects of cannabis on sleep and the treatment of insomnia symptoms remains. The optimal type, concentration, ratio, and dosage form of cannabinoids in the treatment of insomnia symptoms needs further clarification. As the trend of acceptance and use of cannabis continues, more high quality evidence to help guide clinicians in their recommendations will hopefully become available.
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