A HOF-based electrochemical aptasensor for highly sensitive and selective detection of trace oxytetracycline

Hydrogen organic frameworks (HOFs) are a novel class of porous crystalline materials, which have attracted lots of attention in various applications. Nevertheless, HOFs-based electrochemical aptasensors have not been reported so far. In this work, we successfully constructed an electrochemical aptasensor based on HOFs constructed by 1,3,6,8-tetrakis[p-benzoic acid]pyrene. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to demonstrate the electrochemical performance of the as-synthesized HOF-based electrochemical aptasensorfor the sensitive and selective detection of oxytetracycline.