化学
选择氟
指示
草酸盐
吡啶
自由基离子
自由基环化
光化学
有机化学
催化作用
离子
作者
Haralds Baunis,Bartholomäus Pieber
标识
DOI:10.1002/ejoc.202300769
摘要
Abstract We present a photon‐ and metal‐free approach for the radical fluorination of aliphatic oxalate‐activated alcohols. The method relies on the spontaneous generation of the N ‐(chloromethyl)triethylenediamine radical dication, a potent single electron oxidant, from Selectfluor and 4‐(dimethylamino)pyridine. The protocol is easily scalable and provides the desired fluorinated products within only a few minutes reaction time.
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