材料科学
纳米孔
纳米结构
抗菌活性
纳米技术
同种类的
丝带
细菌
复合材料
生物
遗传学
热力学
物理
作者
Chaoyang Wang,Shengli Zhu,Yanqin Liang,Chunling Qin,Fang Wang,Hao Wang,Chuntao Chang,Akihisa Inoue
标识
DOI:10.1016/j.jcis.2023.04.153
摘要
The biomedical field has the potential to significantly benefit from the use of flexible free-standing Ag nanostructures due to their outstanding mechanical and antibacterial properties. However, the intricate process of synthesizing these nanostructures, as well as the potential toxicity of nanostructured Ag, pose significant challenges. This study used a facile etching method to synthesize the free-standing nanoporous Ag (NP-Ag) ribbons with a homogeneous and bicontinuous three-dimensional ligament structure. The free-standing NP-Ag ribbons demonstrated stable mechanical performance and excellent flexibility when subjected to various deformation states on artificial fingers. Additionally, the NP-Ag ribbons exhibited remarkable antibacterial capacity with rates of 99.81 ± 0.14% against Escherichia coli, 96.11 ± 1.49% against Staphylococcus aureus, and 95.37 ± 1.24% against methicillin-resistant Staphylococcus aureus. The antibacterial mechanism of NP-Ag is attributed to the rapid release of Ag ions (Ag+) in 24 h, causing damage to the bacterial membrane. Moreover, the in vivo results demonstrate that the NP-Ag ribbons provide rapid antibacterial efficacy and are biosafe due to the long-term stable Ag+ release of NP-Ag. The development of these free-standing flexible NP-Ag ribbons offers a new avenue for wearable antibacterial applications.
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