趋化因子
效应器
背景(考古学)
免疫学
先天免疫系统
细胞生物学
骨关节炎
促炎细胞因子
免疫
衰老
医学
生物
炎症
免疫系统
病理
古生物学
替代医学
作者
M.H. van den Bosch,P.L.E.M. van Lent,P.M. van der Kraan
标识
DOI:10.1016/j.joca.2020.01.016
摘要
Inflammatory changes are observed in affected joints of osteoarthritis (OA) patients and are thought to be involved in the pathology that develops along OA progression. This narrative review provides an overview of the various cell types that are present in the joint during OA and which alarmins, cytokines, chemokines, growth factors, and other mediators they produce. Moreover, the involvement of more systemic processes like inflammaging and its associated cellular senescence in the context of OA are discussed.
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