A review of organophosphate flame retardants and plasticizers in the environment: Analysis, occurrence and risk assessment

Organophosphate esters (OPEs) are used as additives in flame retardants and plasticizers. Due to phase out of several congeners of polybrominated diphenyl ethers (PBDEs), the application of organophosphorus flame retardants (OPFRs) is continuously increasing over the years. As a consequence, large amounts of OPEs enter the environment. Sewage and solid waste (especially e-waste) treatment plants are the important sources of OPEs released to the environment. Other sources include emissions of OPE-containing materials and vehicle fuel into the atmosphere. OPEs are widely detected in air, dust, water, soil, sediment and sludge. To know the pollution situation of OPEs, a variety of methods on their pretreatment and determination have been developed. We discussed and compared the analytical methods of OPEs, including extraction, purification as well as GC- and LC-based determination techniques. Much attention has been paid to OPEs because some of them are recognized highly toxic to biota, and the toxicological investigations of the most concerned OPEs were summarized. Risk assessments showed that the aquatic and benthic environments in some regions are under considerable ecological risks of OPEs. Finally, we pointed out problems in the current studies on OPEs and provided some suggestions for future research.