基因组
基因
生物
地图集(解剖学)
后悔
基因组不稳定性
计算生物学
遗传学
计算机科学
DNA
古生物学
DNA损伤
机器学习
作者
Lawrence A. Donehower,Thierry Soussi,Anil Korkut,Yuexin Liu,André Schultz,María Fernanda Peralta Cárdenas,Xubin Li,Özgün Babur,Teng-Kuei Hsu,Olivier Lichtarge,John N. Weinstein,Rehan Akbani,David A. Wheeler
出处
期刊:Cell Reports
[Cell Press]
日期:2019-09-01
卷期号:28 (11): 3010-3010
被引量:114
标识
DOI:10.1016/j.celrep.2019.08.061
摘要
(Cell Reports 28, 1370–1384.e1–e5; July 30, 2019) In the originally published version of this article, The Cancer Genome Atlas (TCGA) Network was listed as an author because all of the analyses were based on TCGA data. However, because this paper was not officially authorized by the TCGA Network, we have now removed The Cancer Genome Atlas Network as an author. The authors regret this error. Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome AtlasDonehower et al.Cell ReportsJuly 30, 2019In BriefDonehower et al. performed a comprehensive analysis of the effects of TP53 gene mutation in 32 cancer types and 10,225 patients from The Cancer Genome Atlas (TCGA). Data synthesized from five different analysis platforms show how mutant TP53 increases genomic instability and induces major pathway signaling changes in cancer cells. Full-Text PDF Open Access
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