Delivery to mitochondria: a narrower approach for broader therapeutics

Introduction: Research has revealed a relationship between mitochondrial dysfunction and diseases such as diabetes, ischemia–reperfusion injury, cancer and many more. As a result, mitochondria have gained attention as a target organelle for the treatment of many diseases. Successful delivery of the drug molecule to the mitochondria could be achieved by keeping in mind the normal intracellular trafficking fate of molecules in cell as well as through the mitochondria and exploring the new possibilities to reach the target in an efficient manner.