Highly Efficient and Versatile Synthesis of Some Important Precursors from 1,6‐Anhydrous‐β‐D‐glucopyranose as a Green Starting Material

Abstract Some important precursors (1,6‐anhydrous‐2‐deoxy‐2‐azido‐β‐D‐glucopyranose (3), 1,6‐anhydrous‐2‐deoxy‐2‐ azido‐3,4‐di‐O‐benzyl‐β‐D‐mannopyranose (5), 1,6:2,3‐dianhydrous‐β‐D‐glucopyranose (6), 1,6‐anhydrous‐3‐deoxy‐3‐azido‐β‐D‐glucopyranose (10) and 1,6‐anhydrous‐2,4‐di‐O‐benzoyl‐β‐D‐glucopyranose (11)) for complex oligosaccharide synthesis were readily prepared from a green starting material 1,6‐anhydrous‐β‐D‐glucopyranose in one or two steps with moderate to high yields. These improved methods established herein will greatly facilitate the assembly of some complex oligosaccharides for the biological study.