基质血管部分
医学
临床试验
关节病
外科
人口
疾病
动物研究
间质细胞
物理疗法
骨关节炎
病理
内科学
替代医学
环境卫生
作者
Yuan Liu,Liping Huang,Yi Zeng,Mingyang Li,Huiqi Xie,Bin Shen
标识
DOI:10.1007/s11427-021-2090-3
摘要
Autologous fat-derived stromal vascular fraction (SVF) is a mixed cell population that has been used for many years in regenerative plastic surgery. In terms of animal and clinical research, this concise review was performed to evaluate the efficacy of SVF in knee degenerative joint disease (KDJD), which could cause pain, disability and severely affect patients' lives. Thirteen studies retrieved and screened from the databases were included, including six animal studies and seven clinical trials. The meta-analysis of clinical research shows that intra-articular injection of SVF, in combination with adjuvant surgery, could alleviate pain and improve early functional recovery for patients with KDJD at Kellgren-Lawrence (KL) grades II-III.
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