费斯特共振能量转移
单分子微动
生物分子
能量转移
化学
生物物理学
动力学(音乐)
分子
化学物理
物理
生物
生物化学
荧光
声学
量子力学
有机化学
作者
Mai T. Huynh,Bhaswati Sengupta
出处
期刊:Biophysica
[MDPI AG]
日期:2022-06-06
卷期号:2 (2): 123-134
被引量:1
标识
DOI:10.3390/biophysica2020014
摘要
Single-molecule Förster resonance energy transfer (smFRET) enables the deconvolution of various conformational substates of biomolecules. Over the past two decades, it has been widely used to understand the conformational dynamics of enzymes. Commonly, enzymes undergo reversible transitions between active and inactive states in solution. Using smFRET, the details of these transitions and the effect of ligands on these dynamics have been determined. In this mini-review, we discuss the various works focused on the investigation of enzyme conformational dynamics using smFRET.
科研通智能强力驱动
Strongly Powered by AbleSci AI