This paper describes the basic knowledge of reconfigurable manufacturing systems and axiomatic design,the reconfigurable manufacturing systems through two axioms(independence axiom and the information axiom) of the axiomatic design are designed.We put up the four levels of decomposition of the overall goal in the application of the independence axiom,each level of decomposition is completed in four steps,and their design equations are listed.Then we list the summary of the corresponding functional structure table;the system's information content is calculated in the complexion of non-coupling design and quasi-coupled design in the application of the information axiom.Finally,the design problems and corresponding solutions of the two axioms of axiomatic are put forward.