Resistance of Pseudomonas aeruginosa and Its Chlorhexidine-sulfadiazine-resistant Gene

OBJECTIVE To investigate the resistance of Pseudomonas aeruginosa isolated from two hospitals and its chlorhexidine-sulfadiazine-resistant genes(qacE△1-sul1). METHODS Microdilution tests were performed to detect the susceptibility of 66 strains of P.aeruginosa to 6 kinds of antimicrobial agents.The qacE△1-sul1 gene was analyzed by PCR. RESULTS The resistant rates to other antimicrobial agents were between 12.5-87.5%.qacE△1-sul1 gene was 50.0%. CONCLUSIONS The 66 strains are multiple-drug-resistant.There are very high positive percentages of qacE△1-sul1 gene in P.aeruginosa isolated from two hospitals.