Visible-light induced direct C-H difluoromethylation of quinoxalin-2(1H)-ones by [bis(difluoroacetoxy)iodo]benzene under catalysis-free conditions

Abstract Visible light-induced direct C-H difluoromethylation of quinoxalin-2(1H)-ones by employing [bis(difluoroacetoxy)iodo]benzene as a difluoromethylation reagent is reported for the first time. The inexpensive and readily accessible reagents and the catalysis-Free reaction conditions render this method an alternative and practical strategy for the synthesis of C3-difluoromethylated quinoxalin-2(1H)-ones.