[Chinese expert consensus on non-traditional blood lipid parameters to control the risks of arteriosclerotic cardiovascular disease].

Atherosclerotic cardiovascular disease is the general name of a series of diseases based on atherosclerosis. With the development of the social economy and the progress of population aging in China, the burden of atherosclerotic cardiovascular disease is increasing. However, in recent years some clinical studies have proved that the traditional blood lipid indicators, including low-density lipoprotein cholesterol, have some limitations in the risk control of atherosclerotic cardiovascular disease, and the blood lipid indicators need to be further supplemented and improved. This consensus expounds non-traditional blood lipid indexes from the perspectives of test and clinic, mainly including apolipoprotein B and lipoprotein a, non-high density lipoprotein cholesterol and lipoprotein residue, and non-fasting blood lipid. This consensus systematically expounds the pathophysiological mechanism of non-traditional blood lipid indexes, the relationship with cardiovascular disease, detection methods and performance, intervention, control and application in the state of cardiovascular disease, and gives the corresponding clinical expert suggestion.动脉粥样硬化性心血管疾病是以动脉粥样硬化为病理基础的一系列疾病的总称，随着中国社会经济的发展和人口老龄化的进展，动脉粥样硬化性心血管疾病负担日益加重。近年来一些临床研究证明，包括低密度脂蛋白胆固醇在内的传统血脂指标在动脉粥样硬化性心血管疾病的风险管控方面表现出一定的局限性，血脂指标还需进一步补充完善。本共识从检验和临床两个角度系统阐述了非传统血脂指标，主要包括载脂蛋白B和脂蛋白a、非高密度脂蛋白胆固醇和脂蛋白残粒及非空腹血脂。对非传统血脂指标的病理生理机制、与心血管疾病之间的关系、检测方法及性能、以及在动脉粥样硬化性心血管疾病风险管理中的应用进行了系统阐述，并给出了相应的临床专家指导意见。.