Abstract A myelopathy is a disorder of the spinal cord. The symptoms and signs of myelopathy can vary depending on which part of the spinal cord is affected and on the cause of the myelopathy. Certain causes of myelopathy tend to affect distinct areas of the spinal cord. The severity of myelopathies can vary even when the causes are identical. This chapter reviews the clinical features and evaluation of myelopathies in general and the specific forms of myelopathy.