Cross‐Dehydrogenative Coupling Reactions between Phenols and Hetarenes: Modern Trends in Cross‐Coupling Chemistry of Phenols

Abstract Phenol derivatives are widespread as important building blocks in various pharmaceuticals, agrochemicals and materials. Modern economy requires development of “green” methodologies that improve the efficiency of their use and reduction of waste. One such method is the C−H/C−H cross‐coupling, also known as the cross‐dehydrogenative coupling reaction. In this review article, we have summarised the C−H/C−H cross‐coupling reactions of phenols with five‐ and six‐membered heterocyclic compounds, systemised methods of activation of phenol or coupling partner. We discuss these advances with the goal of motivating increased interest to develop novel methodologies in this field of organic chemistry. magnified image