易普利姆玛
医学
结肠炎
小肠结肠炎
内科学
黑色素瘤
肠道菌群
肿瘤科
免疫系统
不利影响
免疫检查点
胃肠病学
免疫学
免疫疗法
癌症
癌症研究
作者
Nathalie Chaput,P. Lepage,Clélia Coutzac,E. Soularue,K. Le Roux,C. Monot,L. Boselli,E. Routier,Lydia Cassard,M. Collins,T. Vaysse,L. Marthey,A. Eggermont,V. Asvatourian,E. Lanoy,C Mateus,C. Robert,F. Carbonnel
标识
DOI:10.1093/annonc/mdz224
摘要
Ann Oncol 2017; 28(6): 1368–1379 (doi: 10.1093/annonc/mdx108) In the original article, there were errors in Figure 3B and the accompanying legend. These have been corrected online as below. Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumabAnnals of OncologyVol. 28Issue 6PreviewIpilimumab, an immune checkpoint inhibitor targeting CTLA-4, prolongs survival in a subset of patients with metastatic melanoma (MM) but can induce immune-related adverse events, including enterocolitis. We hypothesized that baseline gut microbiota could predict ipilimumab anti-tumor response and/or intestinal toxicity. Full-Text PDF Open Archive
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