化学
过硫酸盐
选择性
级联
芳基
单晶
光化学
有机化学
结晶学
催化作用
色谱法
烷基
作者
Yi Ren,Qianqian Yan,Yang Li,Yongjun Gao,Jihe Zhao,Lijun Li,Zhong‐Quan Liu,Zejiang Li
标识
DOI:10.1021/acs.joc.2c00623
摘要
Persulfate-promoted radical cascade trifluoromethylthiolation of aryl acetylenes with AgSCF3 provides a simple reaction system for the synthesis of SCF3-substituted dibenzazepines or dioxodibenzothiazepines with good Z/E selectivity. The single-crystal X-ray diffraction data confirms the structures of the final products. A series of scaled-up experiments, further transformations, and radical inhibition experiments were operated in the reaction system.
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