化学
碘
区域选择性
碘化物
功能群
硫氰酸盐
电泳剂
组合化学
五氧化二铁
有机化学
催化作用
钒
聚合物
作者
Yong-Hao Wang,Yun‐Qian Zhang,Chen-Fan Zhou,You-Qin Jiang,Yue Xu,Xiaobao Zeng,Gong‐Qing Liu
摘要
A simple and efficient method for the regioselective selenation of electron-rich arenes by employing non-metal inorganic iodine pentoxide (I2O5) as a reaction promoter under ambient conditions has been developed. The present protocol showed broad functional group tolerance and easy-to-operate and time-economical features. Additionally, this protocol also allows access to 3-seleno and 3-thiocyanoindoles by the use of readily available selenocyanate and thiocyanate salts. A mechanistic study indicated that the transformation operated through selenenyl iodide-induced electrophilic substitution processes.
科研通智能强力驱动
Strongly Powered by AbleSci AI