细菌性阴道病
医学
衣原体
鳞状上皮内病变
人乳头瘤病毒
人乳头瘤病毒
病因学
混淆
相关性
妇科
内科学
肿瘤科
生理学
癌症
免疫学
宫颈癌
宫颈上皮内瘤变
几何学
数学
作者
G Vetrano,Alessandro Pacchiarotti,Giuseppe Lombardi,V. Cimellaro,Monica Verrico,Simona Carboni,R Corosu
出处
期刊:PubMed
日期:2007-01-01
卷期号:28 (4): 310-2
被引量:5
摘要
Bacterial vaginosis (BV) is a condition that seldom occurs in prepuberal girls or postmenopausal women, suggesting a hormonal component in its aetiology. The precise mechanisms by which BV arises are not fully understood. One proposed mechanism suggests that carcinogenic nitrosamines act either independently or via human papilloma virus (HPV). Human papillomavirus is known to be associated with the development of squamous intraepithelial lesion (SIL). Still today the relationship between BV and SIL is debated. Many confounding factors regarding the relationship between BV and SIL include the presence of HPV and/or other sexually transmitted diseases. In a case-controlled study the correlation between BV, SIL and the presence of HPV was evaluated. BV was diagnosed according to standard criteria: vaginal pH > 4.5; positive amine test or 'whiff' test; presence of clue cells and abnormal discharge. High risk-HPV testing by PCR was performed. X2 Pearson analysis was applied for statistical evaluation of data. The results of the study have shown that BV is not associated with SIL.
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