雌激素
雌激素受体
医学
兴奋剂
核受体
雌激素受体
药理学
内分泌学
内科学
受体
生物
生物化学
转录因子
癌症
基因
乳腺癌
作者
Christian J. Gruber,Walter Tschugguel,Christian Schneeberger,Johannes Huber
摘要
Estrogens and estrogen-like substances are widely distributed in animals and plants, and it is now clear that estrogens have both nuclear and nonnuclear actions. This review article summarizes the production, metabolism, and actions of estrogens, with particular attention to the nuclear actions of estrogens and the mechanisms that underlie the different estrogen-agonist and estrogen-antagonist actions of selective estrogen-receptor–modulating drugs.
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