化学
二硫醇
立体化学
金属
组合化学
药物化学
有机化学
作者
Xiaobing Liu,Wenxin Lv,Junjie Dong,Zekai Liu,Hao Feng,Cong‐Ying Zhou,Yao Zhou
标识
DOI:10.1002/adsc.202301504
摘要
A metal‐free cyclization of benzo[c][1,2]dithiol‐3‐ones and amidines is demonstrated herein. Triphenylphosphine was harnessed as the activating reagent to facilitate the ring‐opening of benzo[c][1,2]dithiol‐3‐ones via S‐S bond cleavage. This PPh3‐Promoted cyclization reaction of benzo[c][1,2]dithiol‐3‐ones enabled to forge a diverse array of 1,3‐benzothiazones in good yields with wide substrate scope under mild conditions.
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