Ultrahigh-permeance polyamide thin-film composite membranes enabled by interfacial polymerization on a macro-porous substrate toward organic solvent nanofiltration

Organic solvent nanofiltration (OSN) membranes have become a powerful separation platform in a myriad of chemical and pharmaceutical fields owing to their superior merits in high separation efficiency and low energy consuming. Despite extensive progress in exploiting polyamide thin film composite (TFC) membranes for OSN, they are heavily limited by inferior solvent permeability, especially when using conventional low-porous polyimide as TFC substrate. Herein, we report a facile substrate engineering strategy to leverage macro-porous Nylon66 microfiltration membrane to replace the conventional low-porous polyimide substrates for fabricating TFC membranes by interfacial polymerization, enabling high and robust solvent permeability during OSN. Distinct from conventional polyimide, Nylon66 substrates take advantage of their high porosity, macro-porous size and excellent hydrophilicity to realize more monomers storage and uniform monomers distribution, allowing to create crumpled and defect-free polyamide layers. With this method, the polyamide TFC membranes show a 2.1-fold increase in ethanol permeance (up to 16.0 L h−1 m−2 bar−1) meanwhile possessing 98 % rejection of dye, surpassing the most reported TFC membranes. We also demonstrate that the TFC membranes exhibit excellent long-term stability in both polar and non-polar solvent, as well as hold huge promise in the precise separation of dye mixture, pharmaceutical ingredient, and catalyst.