嵌合抗原受体
汽车T细胞治疗
计算生物学
细胞疗法
细胞
T细胞
生物
遗传学
免疫系统
作者
Nicholas J. Haradhvala,Marcela V. Maus
出处
期刊:Blood cancer discovery
[American Association for Cancer Research]
日期:2024-02-07
卷期号:5 (2): 86-89
标识
DOI:10.1158/2643-3230.bcd-23-0212
摘要
Single-cell RNA sequencing has emerged as a powerful technique to understand the molecular features of chimeric antigen receptor (CAR) T cells that associate with clinical outcomes. Here we discuss the common themes that have emerged from across single-cell studies of CAR T-cell therapy, and summarize the challenges in interpreting this complex data type.
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