Low-Dose CT Screening in East Asian Women Who Have Never Smoked: Association between Family History of Lung Cancer and Ground-Glass Nodule Prevalence and Growth

In East Asian women who had never smoked and who underwent low-dose CT screening, family history of lung cancer (FHLC) was associated with an increased prevalence of persistent and multiple ground-glass nodules (GGNs), including proven adenocarcinomas; FHLC was an independent risk factor for GGN growth over a 10-year period.