动脉硬化
医学
有氧运动
物理疗法
脉冲波速
荟萃分析
心理干预
随机对照试验
严格标准化平均差
物理医学与康复
内科学
血压
精神科
作者
Irene Sequí‐Domínguez,Dimitris Mavridis,Iván Cavero‐Redondo,Alicia Saz‐Lara,Vicente Martínez Vizcaíno,Sergio Núñez de Arenas‐Arroyo
标识
DOI:10.1136/bjsports-2022-106285
摘要
Arterial stiffness is an early and detectable marker of vascular changes leading to atherosclerotic cardiovascular disease (ACVD). Our objective was to compare the effectiveness of different types of exercise in reducing arterial stiffness in children and adolescents.A systematic review and network meta-analysis (NMA) was conducted including experimental studies reporting the effects of exercise interventions on pulse wave velocity (PWV) in children and adolescents.Cochrane Central Register of Controlled Trials, EMBASE (via Scopus), PubMed (via Medline) and Web of Science from database inception to 25 March 2022.Experimental studies reporting the effects of exercise interventions on PWV in children and adolescents.Fourteen studies were included in the NMA, all of them were randomised controlled trials except one quasi-experimental study, with an overall risk of bias of some concern. Regarding PWV reduction, all exercise modalities were more effective than control, with standardised mean difference ranging from -1.93 (95% CI: -2.84 to -1.02) and -1.11 (95% CI: -2.01 to -0.21) for aerobic exercise and high intensity interval training (HIIT), respectively, to -0.59 (95% CI: -1.39 to 0.22) for combined exercise. Only sensorimotor training was not superior to the control group 0.11 (95% CI: -1.10 to 1.32).Our results support that exercise interventions, especially aerobic exercise or HIIT, can improve arterial stiffness at early ages. The potential to address ACVD early and mitigate long-term consequences via exercise interventions in children and adolescents with higher arterial stiffness requires further investigation.CRD42022322536.
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