Suzuki Coupling in Tröger's Bases: Overcoming Challenging Substrates through Aqueous Micellar Catalysis

Abstract Herein we report the arylation of Tröger's base via the Suzuki cross‐coupling reaction through aqueous micellar catalysis. The developed reaction conditions enabled us to prepare a variety of different derivatives with Tröger's base skeleton, using a low catalytic loading of the readily available Pd(OAc) 2 catalyst and under environmentally friendly aqueous conditions.