A Glycosyl-Imprinted Sensor Used for Accurate Classification and Quantification of Breast Cancer-Derived Exosomes by Electrochemiluminescence Detection of Two Glycoproteins at Dual Potentials

-MUC1, respectively. Based on the simultaneous analysis of the coexistence-specific markers PD-L1 and MUC1 carried by breast cancer-derived exosomes by the GIP sensor, the selectivity for the identification of breast cancer-derived exosomes was improved, thereby greatly expanding the ability of glycosyl imprinting technology to identify breast cancer-derived exosomes and accurately distinguish breast cancer patients from healthy individuals, reducing the risk of false positives and providing a reliable tool for the clinical diagnosis of breast cancer.