Rh(III)‐Catalyzed Dual C─H Annulation of Isoquinolones and 1,6‐Diynes: Access to Naphtho‐Fused Polycyclic Derivatives

Abstract Transition metal‐catalyzed annulations of unsaturated systems through dual C─H activation represent a straightforward tool to access multi cyclic scaffolds. We disclose herein, a Rh(III)‐catalyzed weakly coordinating inherent functional group assisted dual C─H annulation of isoquinolones with 1,6‐diynes. Some necessary control experiments were conducted to untangle the reaction mechanism.