fNIRS Biomarkers for Stratifying Poststroke Cognitive Impairment: Evidence From Frontal and Temporal Cortex Activation

This study revealed that individuals with PSCI exhibited significantly reduced cortical activation in the L-DPFC compared with healthy controls. fNIRS features, particularly L-DPFC centroid values combined with clinical variables, effectively stratify PSCI severity. These findings may inform individualized rehabilitation strategies.