Dual-surface substrate for in situ wearable surface-enhanced Raman spectroscopy (Conference Presentation)

Wearable sensor technology is a powerful tool, but conventional wearable sensors cannot perform simultaneous chemical sensing of multiple biomarkers in biofluids such as sweat and saliva because they are typically sensitive to only one type of chemical in an analyte at a time. Here we present a wearable dual-surface substrate for in situ surface-enhanced Raman spectroscopy (SERS). The substrate is composed of a gold nanomesh structure that can be tailored into any shape and attached to virtually any surface. Notedly, SERS can be performed on both surfaces of the substrate, highly effective for multiplexed in situ chemical sensing of biofluids.