Enantio- and regioselective nickel/photoredox-catalyzed cross-electrophile coupling of benzylic aziridines with alkynyl bromides.

-amino acids. Mechanistic studies were indicative of the aziridine being activated through a regioselective nucleophilic halide ring opening and subsequent enantioselective XEC of the generated β-amino benzyl halides with alkynyl bromides.