Mung bean as a potent emerging functional food having anticancer therapeutic potential: Mechanistic insight and recent updates

绿豆 生物技术 癌变 生物 豆类 功能性食品 癌症 食品科学 植物 遗传学
作者
Nirmala Sehrawat,Mukesh Yadav,Sunil Kumar,Ashwanti Devi,Rajbir Singh,Varruchi Sharma,Kuldeep Dhama,José M. Lorenzo,Añil Sharma
出处
期刊:Biotechnology and Applied Biochemistry [Wiley]
卷期号:70 (6): 2002-2016 被引量:1
标识
DOI:10.1002/bab.2505
摘要

Abstract Cancer is still a major challenge for humans. In recent years, researchers have focused on plant‐based metabolites as a safe, efficient, alternative or combinatorial, as well as cost‐effective preventive strategy against carcinogenesis. Mung bean is an important nutritious legume, and known for providing various health benefits due to various bioactive phytochemicals and easily digestible proteins. Regular intake of mung bean helps to regulate metabolism by affecting the growth and survival of good microbes in the host gut. Mung bean has also been reported to have anti‐inflammatory, antioxidant, antiproliferative, and immunomodulatory properties. These properties may possess the preventive potential of mung bean against carcinogenesis. Bibliographic databases for peer‐reviewed research literature were searched through a structured conceptual approach using focused review questions on mung beans, anticancer, therapeutics, and functional foods along with inclusion/exclusion criteria. For the appraisal of the quality of retrieved articles, standard tools were employed. A deductive qualitative content analysis methodology further led us to analyze outcomes of the research and review articles. The present review provides recent updates on the anticancer potential of mung bean and the possible mechanism of action thereof to prevent carcinogenesis and metastasis. Extensive research on the active metabolites and mechanisms of action is required to establish the anticancer potential of mung bean. Keeping the above facts in view, mung bean should be investigated for its bioactive compounds, to be considered as functional food of the future.
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