WCN24-1041 OXIRIS MEMBRANE PERFORMANCE IN PATIENTS WITH SEPTIC SHOCK AND CONTINUOUS KIDNEY REPLACEMENT THERAPY REQUIREMENT: A RANDOMIZED CONTROLLED TRIAL

The highly selective semipermeable Oxiris membranes have shown to provide endotoxin adsorption and removal of different inflammatory cytokines which could improve hemodynamic stability in patients with septic shock and continuous kidney replacement therapy (CKRT) requirement. The aim of this study was to compare the clinical efficacy of CKRT using an Oxiris membrane to maintain the mean arterial pressure (MAP) >65mmHg, after 72 hours of treatment, with a lower vasopressor dose than the use of a conventional AN69 standard membrane.