Production of 225Ac for medical application from 232Th-metallic targets in Nb-shells irradiated with middle-energy protons

A method for large-scale production of prospective medical radionuclide 225 Ac including irradiation of a massive metallic 232 Th-target in Nb-shell with 160 MeV-protons and original procedure of highly purified 225 Ac isolation has been developed.