医学
胸腔积液
放射科
活检
超声波
恶性胸腔积液
气胸
胸膜疾病
前瞻性队列研究
呼吸道疾病
外科
肺
内科学
作者
Mingming Deng,Xianwei Ye,Jiangwei Ma,Xinglun Yang,Qin Zhang,Bin Jiang,Jie Wu,Qing Wen,Y C Zheng,Yulong Yin,Run Tong,Guimei Zhou,Hongmei Yao,Xuelian Li,Felix J.F. Herth,Gang Hou,Chen Wang
出处
期刊:Annals of the American Thoracic Society
[American Thoracic Society]
日期:2023-09-01
卷期号:20 (9): 1242-1249
被引量:4
标识
DOI:10.1513/annalsats.202212-1047oc
摘要
Rationale: The diagnostic yield of traditional ultrasound-guided pleural biopsy remains unsatisfactory, particularly when the pleural thickness is ⩽5 mm and/or no pleural nodules are detected. Pleural ultrasound elastography (UE) has a better diagnostic yield than traditional ultrasound for malignant pleural effusion (MPE). However, studies on UE-guided pleural biopsies are lacking. Objectives: To evaluate the feasibility and safety of UE-guided pleural biopsy. Methods: In this multicenter prospective single-arm trial, patients with pleural effusion whose pleural thickness was ⩽5 mm with no pleural nodules were enrolled between July 2019 and August 2021. The diagnostic yield of UE-guided pleural biopsy for pleural effusion and its sensitivity for detecting MPE were evaluated. Results: Ninety-eight patients (mean age, 62.4 ± 13.2 yr; 65 men) were prospectively enrolled. The diagnostic yield of UE-guided pleural biopsy for making any diagnosis was 92.9% (91/98), and its sensitivity for MPE was 88.7% (55/62). In addition, its sensitivity for pleural tuberculosis was 69.6% (16/23). The rate of postoperative chest pain was acceptable, and there was no pneumothorax. Conclusions: UE-guided pleural biopsy is a novel technique for diagnosing MPE with good diagnostic yield and sensitivity. Clinical trial registered with https://www.chictr.org.cn (ChiCTR2000033572).
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