Association of Cumulative Blood Pressure With Progression of Depressive Symptoms and Functional Impairment Among Adults Aged 50 Years or Older: 10-Year Follow-up of 2 Longitudinal Cohorts

Elevated cumulative BP was associated with accelerated aggravation of depressive symptoms and functional impairment, suggesting that controlling systolic BP and pulse pressure while maintaining adequate diastolic BP is of paramount importance for adults to achieve health longevity.