Chiral Ligands with 1,10-Phenanthroline Scaffold for Copper-Catalyzed Enantioselective C(sp3)−H Bond Amidation

We herein report newly developed C₂-symmetric 2,9-diarylphenanthroline ligands with easily modified chiral amide motifs, which enable Cu-catalyzed intramolecular C(sp³)-H amidation of mesylcarbamates to deliver 2-oxazolidone derivatives with up to 88:12 er.