Where should Fenton go for the degradation of refractory organic contaminants in wastewater?

Fenton process has become a research hotspot due to the nonselective and efficient degradation of dissolved organic matter (DOM) by ·OH. However, there are still many challenges and bottlenecks for conventional Fenton (CF). This study provides the first comprehensive insight into the mechanisms of DOM degradation by the Fenton process, including the various subcategories of humic substances, emerging trace contaminants, including persistent organic pollutants, endocrine disrupting chemicals, and pharmaceuticals and personal care products, and the interference of humus and low molecular weight organic acids on the removal of trace contaminants. In addition, a statistical comparison of the economics of CF and three types of Fenton-like technologies (Photo-Fenton, Electro-Fenton, and Ultrasonic-Fenton) is conducted based on existing studies, which can be used as a reference for engineering applications. Moreover, a brief overview of the categories and characteristics of heterogeneous Fenton, which have been extensively studied in recent years, and a comparison of their catalysts are presented. In the end, the paper advances a possible future research direction.