三氟化硼
恶唑
醛
冷凝
硼
化学
三氟化钠
组合化学
有机化学
催化作用
物理
热力学
作者
Vitaly S. Mityanov,Alexandra G. Podrezova,Антон В. Кутасевич,И. С. Пыцкий,Victor N. Khrustalev
标识
DOI:10.1002/slct.202203421
摘要
Abstract A new synthetic protocol for the preparation of oxazole N ‐oxides in the form of stable boron trifluoride complexes has been developed. It is based on the condensation of α‐diketone monooximes with an appropriate aldehyde component in the presence of an equimolar amount of boron trifluoride. The method opens access to a broad scope of derivatives including previously unknown 2‐unsubstituted oxazole N ‐oxides. Its abilities were demonstrated via the synthesis of 25 diverse oxazole derivatives in 14–89 % yields.
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