Metabolic Pathways and Engineering of Polyhydroxyalkanoate Biosynthesis

Abstract Introduction Metabolic Pathways for PHA Biosynthesis Organization of the Genes Involved in PHA Biosynthesis Monomer‐supplying Enzymes for PHA Biosynthesis β‐Ketothiolase (PhaA) Acetoacetyl‐CoA Reductase (PhaB) ( R )‐3‐Hydroxyacyl‐ACP–CoA transferase (PhaG) ( R )‐Specific Enoyl‐CoA Hydratase (PhaJ) Metabolic Engineering and Improvements in PHA Biosynthesis Metabolic Engineering for PHA Production in Recombinant Escherichia coli Metabolic Improvement for PHA Production in Ralstonia eutropha PHB‐4 and Pseudomonads Outlook and Perspectives