Studies on Organophosphorus compounds 87. A Convenient Procedure for the Preparation of Diethyl 2-Oxoalkylphosphonates

Abstract A facile one-pot procedure for the synthesis of diethyl 2-oxoalkylphosphonates is described. It involves an Arbuzov rearrangement of triethylphosphite with 1-bromoketone in which the carbonyl function was masked in the form of benzenesulfonyl hydrazone. Subsequent deprotection via oxidative cleavage affords the title compounds with fair yields.