Preoperative red cell distribution width predicts postoperative cognitive dysfunction after coronary artery bypass grafting

术后认知功能障碍 医学 红细胞分布宽度 围手术期 内科学 心脏病学 优势比 置信区间 接收机工作特性 冠状动脉疾病 麻醉 逻辑回归 动脉 认知 精神科
作者
Jing Wan,Peiwen Luo,Xiaonan Du,Hong Yan
出处
期刊:Bioscience Reports [Portland Press]
卷期号:40 (4) 被引量:23
标识
DOI:10.1042/bsr20194448
摘要

Abstract We assessed the relationship between red blodd cell distribution width (RDW) and postoperative cognitive dysfunction (POCD) after coronary artery bypass grafting (CABG) in patients who usually had obvious hemodynamic changes. We enrolled 362 coronary heart disease patients who received CABG. POCD was assessed through neuropsychological examination at 21 days after operation. Demographics, history of diseases, blood biochemical parameters and perioperative data were collected. The receiver operating characteristic (ROC) curve was used to find the best cut-off value of RDW for diagnosis of POCD. Logistic regression was used to explore the relationship between RDW and POCD. The 21-day incidence of POCD in patients receiving CABG was 27.1% (98/362). The RDW of POCD patients was significantly higher than in the non-POCD patients (17.4 vs. 13.2). The sensitivity and specificity of RDW for predicting POCD were 82.7 and 64.8%, respectively. The POCD patients also tended to be older and had higher fasting plasma glucose, hypersensitive c-reactive protein, tumor necrosis factor-α, white blood cell levels and longer surgery time. No significant differences were found in other parameters. The 21-day neuropsychological test results were better in the POCD patients than the non-POCD patients. After adjustment of potential factors, the preoperative high RDW was still associated with an increased risk of POCD (odds ratio (OR) = 2.52, 95% confidence interval (CI): 1.28–4.31). Our study indicates that preoperative RDW is significantly elevated in POCD patients receiving CABG. The elevated preoperative RDW is associated with an increased risk of POCD and preoperative RDW can be an independent predictor of POCD.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
小月喜欢大福完成签到,获得积分10
1秒前
ABC发布了新的文献求助10
2秒前
2秒前
2秒前
3秒前
3秒前
ww完成签到,获得积分10
4秒前
赘婿应助lee采纳,获得10
4秒前
科研通AI2S应助剑来不来采纳,获得10
6秒前
6秒前
Amazing_Grace发布了新的文献求助10
8秒前
duo关闭了duo文献求助
8秒前
xy发布了新的文献求助10
8秒前
香蕉觅云应助shinn采纳,获得10
8秒前
LLLLL发布了新的文献求助30
8秒前
11秒前
大模型应助mzl采纳,获得10
12秒前
14秒前
15秒前
隐形曼青应助陈江河采纳,获得10
15秒前
luxi0714完成签到,获得积分20
15秒前
16秒前
lwh104完成签到,获得积分0
20秒前
理理完成签到 ,获得积分10
20秒前
fdzzz发布了新的文献求助10
20秒前
21秒前
领导范儿应助彩色飞瑶采纳,获得10
22秒前
23秒前
bobo呀发布了新的文献求助10
24秒前
陈江河发布了新的文献求助10
27秒前
小蚂蚁发布了新的文献求助10
29秒前
可靠馒头完成签到,获得积分10
29秒前
徐鎏洋完成签到 ,获得积分10
36秒前
小慧儿发布了新的文献求助10
37秒前
39秒前
昏睡的傲菡完成签到 ,获得积分10
40秒前
zy发布了新的文献求助10
42秒前
酥瓜完成签到 ,获得积分10
43秒前
44秒前
sun完成签到,获得积分10
45秒前
高分求助中
(禁止应助)【重要!!请各位详细阅读】【科研通的精品贴汇总】 10000
Robot-supported joining of reinforcement textiles with one-sided sewing heads 800
水稻光合CO2浓缩机制的创建及其作用研究 500
Logical form: From GB to Minimalism 500
2025-2030年中国消毒剂行业市场分析及发展前景预测报告 500
The Netter Collection of Medical Illustrations: Digestive System, Volume 9, Part III – Liver, Biliary Tract, and Pancreas, 3rd Edition 400
Elliptical Fiber Waveguides 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4171390
求助须知:如何正确求助?哪些是违规求助? 3706898
关于积分的说明 11695659
捐赠科研通 3392544
什么是DOI,文献DOI怎么找? 1860795
邀请新用户注册赠送积分活动 920545
科研通“疑难数据库(出版商)”最低求助积分说明 832754