黄原酮
生物
植物
真菌
化学
电喷雾电离
圆二色性
立体化学
质谱法
色谱法
作者
Xiao-Ping Peng,Fangjin Sun,Gang Li,Cong Wang,Yuhan Zhang,Changzheng Wu,Chunyang Zhang,Yong Sun,Siyi Wu,Yuxiang Zhang,Hui Zong,Rui Guo,Hongxiang Lou
标识
DOI:10.1021/acs.jafc.1c03513
摘要
Six new xanthone dimers, diaporxanthones A–F (1–6), and an unusual xanthone monomer diaporxanthone G (7), in addition to seven known analogues (8–14), were isolated and identified from endophytic Diaporthe goulteri L17 harbored in the fruits of the salt-tolerant plant Vitex trifolia. The chemical structures of these metabolites were elucidated on the basis of nuclear magnetic resonance, high-resolution electrospray ionization mass spectrometry, and reported data in the literature. Their absolute configurations were established by single-crystal X-ray diffraction analysis together with time-dependent density functional theory electronic circular dichroism calculations. Among these compounds, compounds 1 and 6 exhibited moderate antifungal activities against Nectria sp. and Colletotrichum musae and compound 4 showed significant cytotoxicity against all selected five cancer cell lines.
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