Prostatic tuberculosis is considered to be a rare disease. It is usually associated with nonspecific symptoms and is detected incidentally after prostatic histological analysis. We report the case of a 60-year-old man suffering from acute urinary retention with an estimated 90 g prostate who underwent Holmium laser enucleation of the prostate. The diagnosis of prostate tuberculosis was histological based on the analysis of prostate enucleation chips. The clinical course was favourable under anti-tuberculous drugs.